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Transmission Electron Microscopy (TEM) is a technique used to visualize samples at micro and nanometre scale to study tissues, cells, organelles and macromolecular assemblies. Biological samples has to be processed in order to be visualized in a transmission electron microscope.

Samples can be chemically fixed or cryo-immobilized. Depending the type of fixation used samples will be dehydrated, embedded in resin and sectioned to generate ultrathin sections that will be analysed in the microscope.

In our service at the CPU we receive fixed samples to be processed for TEM and we do the data collection. We are open to receive projects in a “first-come-first-served” basis. Each project will be discussed to stablish a better strategy of sample preparation and data acquisition prior beginning.

The groups will need to submit a form with the project specifications. We will do the sample processing, data collection and delivery the EM images.

Last updated: July 4, 2022